Blood in the urine always deserves evaluation, even when something obvious seems to explain it.

Two kinds

Gross hematuria is visible, and the color can range from pink to tea colored to frankly red.

Microscopic hematuria is found on a urine test rather than seen. It matters just as much.

Why it is taken seriously

Plenty of causes are benign, including infection, stones, an enlarged prostate and vigorous exercise. But blood in the urine is also the most common way bladder cancer announces itself, and bladder cancer is far more treatable when it is found early.

Painless visible blood in the urine is the presentation that most warrants prompt evaluation, precisely because there is no obvious explanation to point at.

What the workup involves

Imaging of the kidneys and ureters, usually with a CT scan, and cystoscopy, which means looking inside the bladder with a thin flexible scope in the office. A urine test for abnormal cells may be added.

The combination is what matters. Imaging alone can miss a bladder tumor, and cystoscopy alone can miss something upstream.

The mistake to avoid

Assuming an infection explains it and never rechecking. If blood was found alongside an infection, it should be rechecked once the infection has cleared. Blood that persists after treatment needs the full evaluation.